Guo Meihua, Lim Jennifer C, Wojcik Eva M
Department of Pathology, Loyola University Medical Center, Maywood, Illinois 60153, USA.
Diagn Cytopathol. 2003 Jul;29(1):28-30. doi: 10.1002/dc.10301.
A Sertoli-Leydig-cell tumor is an exceptionally rare neoplasm. We present the pelvic washing cytomorphology of an ovarian Sertoli-Leydig-cell tumor with a retiform pattern in a 24-yr-old female. The cytologic features in this case were tight tissue fragments composed of small, relatively uniform cells with scanty cytoplasm and small rounded or blunt papillary fragments with hyalinized cores lined with small, mildly atypical cuboidal cells. Differential diagnoses included borderline and well-differentiated papillary serous tumors, clear-cell carcinoma, and collagen balls. Correlation of cytologic findings with histomorphology is crucial for correct interpretation of pelvic washings in cases of Sertoli-Leydig-cell tumors.
支持细胞-间质细胞瘤是一种极为罕见的肿瘤。我们展示了一名24岁女性卵巢支持细胞-间质细胞瘤呈网状结构的盆腔冲洗液细胞形态学特征。该病例的细胞学特征为紧密的组织碎片,由小的、相对均匀的细胞组成,胞质稀少,以及带有玻璃样变核心的小圆形或钝性乳头样碎片,核心内衬有小的、轻度异型的立方体细胞。鉴别诊断包括交界性和高分化乳头状浆液性肿瘤、透明细胞癌和胶原球。在支持细胞-间质细胞瘤病例中,将细胞学发现与组织形态学相关联对于正确解读盆腔冲洗液至关重要。