Targeted therapies for the treatment of leukemia.

OBJECTIVES

To review novel targeted therapies for the treatment of leukemia.

DATA SOURCES

Professional journals, books, and government publications.

CONCLUSION

Nonspecific cytotoxic chemotherapeutic agents provide marginal therapeutic benefit and significant toxicity when used in the treatment of leukemia. There is a tremendous need for new therapies with increased efficacy and decreased adverse effects. Advances in molecular science, genetics, and immunology, along with improved laboratory technology, have led to the discovery of unique targets integral to the growth and proliferation of malignant cells which are providing the foundation for the development of a new generation of antitumor agents.

IMPLICATIONS FOR NURSING PRACTICE

Nurses must be prepared to educate patients, administer novel therapies, and manage side effects.