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预冷和预热程序对骨水泥型髋关节置换术中骨水泥聚合和热致骨坏死的影响。

Effects of pre-cooling and pre-heating procedures on cement polymerization and thermal osteonecrosis in cemented hip replacements.

作者信息

Li Chaodi, Schmid Steven, Mason James

机构信息

Department of Aerospace and Mechanical Engineering, University of Notre Dame, Notre Dame, IN 46556, USA.

出版信息

Med Eng Phys. 2003 Sep;25(7):559-64. doi: 10.1016/s1350-4533(03)00054-7.

Abstract

Numerical studies were performed to investigate bone cement polymerization, temperature history and thermal osteonecrosis in cemented hip replacements with finite element methods. In this paper, the effects of pre-cooling and pre-heating of the prosthesis and/or the cement prior to implantation were simulated. It was found that the cement polymerization initiated near the bone-cement interface and progressed toward the prosthesis when both the cement and prosthesis were initially at room temperature. When the prosthesis and/or cement were pre-cooled, a reduction of the peak temperature at the bone-cement interface resulted, and this may reduce thermal osteonecrosis. However, this also slowed the polymerization process, and may result in a weaker bone cement. If the prosthesis was significantly initially heated, bone cement polymerization reversed reaction direction, started from the cement-prosthesis interface and proceeded toward the bone. Such polymerization direction may reduce or eliminate the formation of voids at the cement-prosthesis interface. Numerical results also showed that pre-heating seemed unlikely to produce significant thermal damage to the bone. The method of pre-heating the prosthesis prior to implantation may decrease the likelihood of cement-prosthesis loosening and increase the life of total hip arthroplasty.

摘要

采用有限元方法进行了数值研究,以探讨骨水泥聚合、温度历程以及骨水泥型髋关节置换术中的热致骨坏死情况。在本文中,模拟了植入前对假体和/或骨水泥进行预冷和预热的效果。研究发现,当骨水泥和假体最初均处于室温时,骨水泥聚合在骨-水泥界面附近开始,并向假体方向推进。当假体和/或骨水泥被预冷时,骨-水泥界面处的峰值温度降低,这可能会减少热致骨坏死。然而,这也会减缓聚合过程,并可能导致骨水泥强度降低。如果假体最初被显著加热,骨水泥聚合反应方向会反转,从骨水泥-假体界面开始并向骨推进。这种聚合方向可能会减少或消除骨水泥-假体界面处孔隙的形成。数值结果还表明,预热似乎不太可能对骨骼产生显著的热损伤。植入前对假体进行预热的方法可能会降低骨水泥-假体松动的可能性,并延长全髋关节置换术的使用寿命。

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