Khadwal Alka, Bharti Bhavneet, Poddar Banani, Basu Srikant, Virdi Virender Singh, Parmar Veena
Department of Pediatrics, Government Medical College and Hospital, Chandigarh, India.
Indian J Pediatr. 2003 May;70(5):439-41. doi: 10.1007/BF02723621.
Bleeding diathesis is a cardinal feature of viperine bite, which has been thought to last not more than 24 hours. There is scarcity of literature about prolonged bleeding disorder in snake envenomation. Various explanations suggested in the literature include-temporary decrease in antivenin levels, rapid elimination of antivenin from circulation or continuous release of unneutralised venom from the envenomated site. Two children with prolonged coagulopathy lasting for more than a week, correction of which required more than 300 ml of antisnake venom are reported here.
出血素质是蝰蛇咬伤的主要特征,一直被认为持续时间不超过24小时。关于蛇咬伤后出血性疾病迁延不愈的文献较少。文献中提出的各种解释包括抗蛇毒血清水平暂时降低、抗蛇毒血清从循环中快速清除或被蛇毒咬伤部位持续释放未被中和的毒液。本文报告了两名儿童患有持续一周以上的凝血障碍,纠正该障碍需要超过300毫升抗蛇毒血清。