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骨质疏松症药物的直接面向消费者的营销与骨密度测定

Direct-to-consumer marketing of osteoporosis drugs and bone densitometry.

作者信息

Hollon Matthew F, Larson Eric B, Koepsell Thomas D, Downer Ann E

机构信息

Department of Medicine, School of Medicine, University of Washington, Seattle, WA, USA.

出版信息

Ann Pharmacother. 2003 Jul-Aug;37(7-8):976-81. doi: 10.1345/aph.1C422.

Abstract

OBJECTIVE

To determine whether there is an association between a woman's exposure to direct-to-consumer (DTC) advertisements for 2 osteoporosis drugs and presentation for bone densitometry.

METHODS

A matched case-control study was conducted between October and December 1998 at an academic primary care clinic in Seattle, WA. Seventeen women from the study population (aged >/=18 y, seen in the previous 2 y at the academic primary care clinic) presented for bone densitometry. All 51 women completed a self-administered questionnaire.

RESULTS

Women familiar with 1 of 2 osteoporosis drugs due to exposure to advertisements had 9 times the odds of densitometry (unadjusted OR 9.3, 95% CI 1.0 to 86). Multivariate analysis, including confounders such as education level and whether a woman had previously had 3 screening tests (mammography, Pap smear, serum cholesterol), revealed a significant and strong association between exposure to advertisements and densitometry (adjusted OR 29, 95% CI 1.6 to 511).

CONCLUSIONS

DTC marketing may increase health services utilization. Further independent evaluation of DTC marketing based on available observational evidence is feasible and warranted.

摘要

目的

确定女性接触两种骨质疏松症药物的直接面向消费者(DTC)广告与进行骨密度测量之间是否存在关联。

方法

1998年10月至12月在华盛顿州西雅图的一家学术初级保健诊所进行了一项匹配病例对照研究。研究人群中有17名女性(年龄≥18岁,在过去2年内在该学术初级保健诊所就诊)进行了骨密度测量。所有51名女性都完成了一份自我管理的问卷。

结果

因接触广告而熟悉两种骨质疏松症药物之一的女性进行骨密度测量的几率是其他女性的9倍(未调整的比值比为9.3,95%置信区间为1.0至86)。多变量分析,包括教育水平以及女性之前是否进行过三项筛查测试(乳房X光检查、巴氏涂片检查、血清胆固醇检查)等混杂因素,显示接触广告与骨密度测量之间存在显著且强烈的关联(调整后的比值比为29,95%置信区间为1.6至511)。

结论

DTC营销可能会增加医疗服务的利用率。基于现有观察证据对DTC营销进行进一步的独立评估是可行且必要的。

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