Guthrie J R, Dennerstein L, Taffe J R, Donnelly V
Office for Gender and Health, Department of Psychiatry, The University of Melbourne, Victoria, Australia.
Climacteric. 2003 Jun;6(2):112-7.
To determine the rate and timing of medical consultations for menopausal problems during the menopausal transition and to identify baseline and prospective variables associated with these consultations.
This was a 9-year community-based study with annual interviews of 438 Australian-born women who at baseline were aged 45-55 years, had menstruated in the previous 3 months and were not using hormone therapy.
In total, 387 women completed the 9-year study, of whom 86% consulted a doctor about menopausal problems, with an annual mean of 31%. Of the women, 212 experienced a natural menopause. The prevalence of consultations regarding menopausal problems was a maximum about 2.5 years before the final menstrual period (FMP). The time of greatest prevalence of reporting bothersome hot flushes was 2.1 years after the FMP. There was no significant relationship between number of symptoms reported and time to/from the FMP. Multiple regression analysis found that an increased number of consultations for menopausal problems was associated with the baseline variables: vasomotor symptoms (p < 0.005), rating one's health as 'worse than most' (p < 0.005) and taking two or more non-prescription medications (p < 0.05); and the follow-up variables: dysphoric symptoms (p < 0.05), vasomotor symptoms (p < 0.005) and hormone therapy use (p < 0.001).
Nearly one-third of women will consult a doctor annually during the years of the menopausal transition. Those who are more symptomatic with mood or vasomotor symptoms consult doctors more often and are more likely to use hormone replacement therapy.
确定围绝经期过渡期间因绝经问题进行医疗咨询的发生率和时间,并识别与这些咨询相关的基线和前瞻性变量。
这是一项为期9年的基于社区的研究,每年对438名澳大利亚出生的女性进行访谈,这些女性在基线时年龄为45 - 55岁,前3个月有月经且未使用激素疗法。
共有387名女性完成了9年的研究,其中86%的女性因绝经问题咨询过医生,年平均咨询率为31%。这些女性中,212人经历了自然绝经。绝经问题咨询的患病率在最后一次月经(FMP)前约2.5年达到最高。报告烦人的潮热最普遍的时间是在FMP后2.1年。报告的症状数量与距FMP的时间之间没有显著关系。多元回归分析发现,绝经问题咨询次数增加与基线变量有关:血管舒缩症状(p < 0.005)、将自己的健康评为“比大多数人差”(p < 0.005)以及服用两种或更多非处方药(p < 0.05);以及随访变量:烦躁症状(p < 0.05)、血管舒缩症状(p < 0.005)和激素疗法使用(p < 0.001)。
在围绝经期过渡的几年中,近三分之一的女性每年会咨询医生。那些情绪或血管舒缩症状更明显的女性更常咨询医生,并且更有可能使用激素替代疗法。