522例不可触及乳腺病变的立体定向细针穿刺抽吸细胞学检查与粗针活检的比较
Comparison of stereotactic fine needle aspiration cytology and core needle biopsy in 522 non-palpable breast lesions.
作者信息
Leifland K, Lagerstedt U, Svane G
机构信息
Department of Radiology, St. Göran Hospital Inc., Stockholm, Sweden.
出版信息
Acta Radiol. 2003 Jul;44(4):387-91. doi: 10.1080/j.1600-0455.2003.00098.x.
PURPOSE
To compare the accuracy of stereotactic fine needle aspiration cytologies (S-FNAC) and stereotactic core needle biopsies (S-CNB) in non-palpable breast lesions.
MATERIAL AND METHODS
Between May 1993 and December 2000, 696 patients with mammographically detected lesions were biopsied both with S-FNAC and S-CNB. S-FNAC was performed with spinal needle 22- or 20-gauge and S-CNB with an automated 14-gauge gun.
RESULTS
Of the 696 patients, 522 (75%) underwent breast surgery with postoperative histopathology. In all, 448 of these 522 women (86%) had malignant and 74 (14%) had benign lesions. S-FNAC revealed cancer in 254 (57%) and probable cancer in 48 (11%) (sensitivity 68%, specificity 99.6%) and S-CNB revealed cancer in 388 (87%) and probable cancer in 18 (4%) (sensitivity 90%, specificity 98.8%) of these 448 patients.
CONCLUSION
S-CNB was more accurate than S-FNAC in the diagnosis of non-palpable breast cancer.
目的
比较立体定向细针穿刺抽吸细胞学检查（S-FNAC）和立体定向粗针活检（S-CNB）对不可触及乳腺病变的诊断准确性。
材料与方法
1993年5月至2000年12月期间，对696例经乳腺钼靶检查发现病变的患者同时进行了S-FNAC和S-CNB检查。S-FNAC使用22号或20号脊椎穿刺针进行，S-CNB使用自动14号活检枪进行。
结果
696例患者中，522例（75%）接受了乳腺手术并进行了术后组织病理学检查。在这522例女性中，共有448例（86%）为恶性病变，74例（14%）为良性病变。在这448例患者中，S-FNAC检出癌症254例（57%），可能癌症48例（11%）（敏感性68%，特异性99.6%），S-CNB检出癌症388例（87%），可能癌症18例（4%）（敏感性90%，特异性98.8%）。
结论
在不可触及乳腺癌的诊断中，S-CNB比S-FNAC更准确。
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