Meo Sultan A
Department of Physiology, College of Medicine, King Khalid University Hospital, PO Box 2925, Riyadh 11461, Kingdom of Saudi Arabia.
Saudi Med J. 2003 Jun;24(6):656-9.
The present study was designed to study the effects of welding fumes on maximal voluntary ventilation (MVV) and to determine its severity in relation to duration of exposure. Additional objective was to reduce the potential health risks of welding workers by providing them with information concerning the hazards of welding fumes.
This study was conducted in the Department of Physiology, Basic Medical Sciences Institute, Jinnah Post Graduate Medical Centre, Karachi, Pakistan in 1999. In this study, the MVV was studied in 50 male control subjects and 50 male arc welding workers and all participants were non-smokers with an age range of 20-60 years. The subjects were matched for age, height, weight and socio-economic status. Maximal voluntary ventilation test was performed by using an electronic spirometer and results were compared by a paired t-test.
Welding workers showed a significant reduction in MVV relative to controls.
We conclude that MVV in welding workers is significantly decreased as compared to their matched controls. Stratification of results by years of welding shows a dose-response effect of years of welding on lung function.
本研究旨在探讨焊接烟尘对最大自主通气量（MVV）的影响，并确定其与暴露持续时间相关的严重程度。另一个目的是通过向焊接工人提供有关焊接烟尘危害的信息，降低他们潜在的健康风险。
本研究于1999年在巴基斯坦卡拉奇真纳研究生医学中心基础医学科学研究所生理学系进行。在本研究中，对50名男性对照受试者和50名男性电弧焊接工人的最大自主通气量进行了研究，所有参与者均为非吸烟者，年龄在20至60岁之间。受试者在年龄、身高、体重和社会经济地位方面进行了匹配。使用电子肺活量计进行最大自主通气测试，并通过配对t检验比较结果。
与对照组相比，焊接工人的最大自主通气量显著降低。
我们得出结论，与匹配的对照组相比，焊接工人的最大自主通气量显著下降。按焊接年限对结果进行分层显示，焊接年限对肺功能有剂量反应效应。
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