正常免疫库中髓鞘特异性、自身攻击性T细胞克隆：其性质与调控。 - Suppr

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超能文献

Myelin specific, autoaggressive T cell clones in the normal immune repertoire: their nature and their regulation.

作者信息

Wekerle H

机构信息

Max-Planck-Institute for Psychiatry, Martinsried, Germany.

出版信息

Int Rev Immunol. 1992;9(3):231-41. doi: 10.3109/08830189209061793.

DOI:10.3109/08830189209061793

PMID:1285063

Abstract

摘要

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Myelin specific, autoaggressive T cell clones in the normal immune repertoire: their nature and their regulation.正常免疫库中髓鞘特异性、自身攻击性T细胞克隆：其性质与调控。

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Antibodies to CD44 and integrin alpha4, but not L-selectin, prevent central nervous system inflammation and experimental encephalomyelitis by blocking secondary leukocyte recruitment.抗CD44和整合素α4而非L-选择素的抗体，通过阻断继发性白细胞募集来预防中枢神经系统炎症和实验性脑脊髓炎。

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