Kim Fernando J, Rha Koon H, Hernandez Fernando, Jarrett Thomas W, Pinto Peter A, Kavoussi Louis R
Brady Urological Institute, Johns Hopkins Medical Institutions, Baltimore, Maryland 21287-2101, USA.
J Urol. 2003 Aug;170(2 Pt 1):408-11. doi: 10.1097/01.ju.0000076017.26789.6a.
We evaluated the short-term morbidity and complications of laparoscopic radical nephrectomy (LRN) compared with laparoscopic partial nephrectomy (LPN).
From May 1998 to May 2002, 114 patients were identified with a single unilateral sporadic renal tumor and a normal contralateral kidney. These individuals had undergone LRN (35) or LPN (79).
The LRN and LPN groups were analyzed for age, sex, American Society of Anesthesiologists score and body mass index. Mean tumor size in patients undergoing LRN and LPN was 2.8 +/- 1.2 (range 0.9 to 4.5) and 2.5 +/- 1.0 cm (range 1 to 4.5), respectively (p = 0.17). There were no differences between the 2 groups in terms of mean hospital stay, blood transfusion or surgical complications. There was no difference in mean preoperative and postoperative serum creatinine in patients in the LPN group. Mean postoperative serum creatinine was significantly higher than the mean preoperative level in patients in the LRN group (1.51 +/- 0.22 vs 1.18 +/- 0.37 mg/ml, range 0.6 to 2.4, p = 0.02). In each group 1 case was converted to open surgery due to bleeding.
LPN is associated with similar postoperative convalescence and complications compared with LRN. The increase in serum creatinine noted in patients undergoing radical extirpation supports the use of LPN when clinically indicated.
我们评估了腹腔镜根治性肾切除术(LRN)与腹腔镜部分肾切除术(LPN)相比的短期发病率和并发症。
1998年5月至2002年5月,114例患者被确诊为单侧散发性肾肿瘤且对侧肾脏正常。这些患者接受了LRN(35例)或LPN(79例)。
对LRN组和LPN组患者的年龄、性别、美国麻醉医师协会评分和体重指数进行了分析。接受LRN和LPN的患者平均肿瘤大小分别为2.8±1.2(范围0.9至4.5)和2.5±1.0 cm(范围1至4.5)(p = 0.17)。两组在平均住院时间、输血或手术并发症方面无差异。LPN组患者术前和术后血清肌酐平均值无差异。LRN组患者术后血清肌酐平均值显著高于术前水平(1.51±0.22对1.18±0.37 mg/ml,范围0.6至2.4,p = 0.02)。每组各有1例因出血转为开放手术。
与LRN相比,LPN术后恢复和并发症相似。根治性切除患者血清肌酐升高支持在临床指征明确时使用LPN。