Rodríguez María Alba, Meza Flores José Luis
Servicio de Gastroenterología del Hospital Nacional Hipólito Unanue, Perú.
Rev Gastroenterol Peru. 2003 Apr-Jun;23(2):115-25.
The ingestion of caustic substances represents a serious problem, often with devastating consequences on the esophagus and the stomach.
45 inpatients at the Hipólito Unanue National Hospital were evaluated between 1996 and 2001, 29 female patients (64.4%) and 16 male patients (35.6%) with an average age of 28 years in a range between 15 and 60 years. The caustic substances ingested were: bleach, 30 patients (66.7%), muriatic acid (hydrochloric acid) 13 patients (28.9%), nitric acid and caustic soda, one patient each (2.2%). Among the women: 24 patients ingested bleach (82.7%) 4 patients, muriatic acid (13.7%) and one patient, caustic soda (3.4%). Among the men: 9 patients took muriatic acid (56.3%) 6 patients, bleach (37.5%) 1 patient, nitric acid (6.25%); 29 patients ingested the caustic substances in pure form (64.4%) and 16 patients diluted with other substances: water, soft or alcoholic drinks, oatmeal (35.5%). The time passed between the ingestion and medical attention was of 104 minutes, with a range of 15 to 360 minutes. The average of total ingested solution was 73 ml., ranging between 10 ml and 170 ml. The reason for the ingestion was a conflict with their spouse, 24 patients (53.4%) family conflict, 13 patients (28.9%) accident, 4 patients (8.9%) psychiatric problems, 3 patients (6.7%) and a monetary factor, 1 patient (2.2%). The signs and symptoms when admitted into the hospital were: abdominal pain, 31 patients (68.9%) nausea, 22 patients (48.9%) vomit, 21 patients (46.7%) mouth cavity pain, 19 patients (42.2%) dysphagia, 14 patients (31.1%) sialorrhea, 14 patients (31.1%) odynophagia, 13 patients (15.6%) sensory disorder, 7 patients (15.6%) dysphonia, 3 patients (6.7%) and cephalea, 1 patient (2.2%). Oral compromise was: normal in 11 patients (24.4%) congestion in 23 patients (51.1%) and erosions in 11 patients (24.1%). Endoscopic lesions found were: grade 0 in 6 patients (13.3%) grade 1 in 21 patients (46.7%) Grade 2A in 7 patients (15.6%) Grade 3B in 2 patients (4.4%).
Adolescents and young adults are the age groups which most suffer of this pathology. Bleach is the most ingested caustic substance (66.7%). Women have a higher risk of ingesting a caustic substance (64.4%). Caustic substances are mostly ingested pure (64.4%). Conjugal conflicts are the main reason for caustic ingestion. Clinical symptoms vary, with abdominal pain being the main discomfort among these patients. Oropharyngeal congestion is the most frequent finding. Esophageal-gastric mucose edema and hyperemia (Zargar 1) are the endoscopic lesions mostly found.
腐蚀性物质的摄入是一个严重问题,常常对食管和胃造成毁灭性后果。
1)确定摄入的主要腐蚀性物质以及食管 - 胃黏膜的损伤情况。2)了解我院这些患者的临床 - 流行病学特征。
1996年至2001年间对希波利托·乌纳努埃国立医院的45名住院患者进行了评估,其中女性患者29名(64.4%),男性患者16名(35.6%),平均年龄28岁,年龄范围在15至60岁之间。摄入的腐蚀性物质有:漂白剂,30例患者(66.7%);盐酸,13例患者(28.9%);硝酸和苛性钠,各1例患者(2.2%)。女性患者中:24例摄入漂白剂(82.7%),4例摄入盐酸(13.7%),1例摄入苛性钠(3.4%)。男性患者中:9例摄入盐酸(56.3%),6例摄入漂白剂(37.5%),1例摄入硝酸(6.25%);29例患者摄入的是纯腐蚀性物质(64.4%),16例患者用其他物质稀释:水、软饮料或酒精饮料、燕麦片(35.5%)。摄入与就医之间的时间间隔为104分钟,范围在15至360分钟之间。摄入溶液的总量平均为73毫升,范围在10毫升至170毫升之间。摄入的原因是与配偶发生冲突,24例患者(53.4%);家庭冲突,13例患者(28.9%);意外,4例患者(8.9%);精神问题,3例患者(6.7%);金钱因素,1例患者(2.2%)。入院时的体征和症状有:腹痛,31例患者(68.9%);恶心,22例患者(48.9%);呕吐,21例患者(46.7%);口腔疼痛,19例患者(42.2%);吞咽困难,19例患者(42.2%);流涎,14例患者(31.1%);吞咽痛,14例患者(31.1%);感觉障碍,13例患者(15.6%);声音嘶哑,7例患者(15.6%);头痛,3例患者(6.7%);头痛,1例患者(2.2%)。口腔损伤情况为:11例患者正常(24.4%),23例患者充血(51.1%),11例患者糜烂(24.1%)。内镜检查发现的病变有:0级,6例患者(13.3%);1级,21例患者(46.7%);2A级,7例患者(15.6%);3B级,2例患者(4.4%)。
青少年和年轻人是受这种病症影响最严重的年龄组。漂白剂是最常摄入的腐蚀性物质(66.7%)。女性摄入腐蚀性物质的风险更高(64.4%)。腐蚀性物质大多以纯态摄入(64.4%)。夫妻冲突是摄入腐蚀性物质的主要原因。临床症状各不相同,腹痛是这些患者的主要不适症状。口咽充血是最常见的发现。食管 - 胃黏膜水肿和充血(扎尔加1级)是最常发现的内镜病变。