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单光子发射计算机断层扫描成像在强迫症及立体定向双侧扣带回前部切开术中的应用

Single photon emission computed tomography imaging in obsessive-compulsive disorder and for stereotactic bilateral anterior cingulotomy.

作者信息

Chang Jin Woo, Kim Chan Hyung, Lee Jong Doo, Chung Sang Sup

机构信息

BK21 Project for Medical Science, Yonsei University College of Medicine, Yonsei University College of Medicine, Seoul, Korea.

出版信息

Neurosurg Clin N Am. 2003 Apr;14(2):237-50. doi: 10.1016/s1042-3680(03)00006-8.

DOI:10.1016/s1042-3680(03)00006-8
PMID:12856491
Abstract

In conclusion, the present study suggests that SPECT, using a sophisticated SPM analysis method, may be useful as a potential diagnostic tool for OCD and a possible predictor of treatment outcome for OCD patients undergoing bilateral anterior cingulotomy. The anterior cingulate gyrus seems to be an important structure in the pathogenesis of OCD symptoms. Furthermore, our operative technique of anterior cingulotomy, featuring a larger lesion, seems to be effective in ameliorating the symptoms of OCD without causing any serious complications.

摘要

总之,本研究表明,使用复杂的统计参数映射(SPM)分析方法的单光子发射计算机断层扫描(SPECT),可能作为强迫症的潜在诊断工具,以及接受双侧扣带回前部切开术的强迫症患者治疗结果的可能预测指标。前扣带回似乎是强迫症症状发病机制中的一个重要结构。此外,我们具有更大损伤范围特点的扣带回前部切开术手术技术,似乎能有效改善强迫症症状且不引起任何严重并发症。

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1
Single photon emission computed tomography imaging in obsessive-compulsive disorder and for stereotactic bilateral anterior cingulotomy.单光子发射计算机断层扫描成像在强迫症及立体定向双侧扣带回前部切开术中的应用
Neurosurg Clin N Am. 2003 Apr;14(2):237-50. doi: 10.1016/s1042-3680(03)00006-8.
2
Cerebral metabolic correlates as potential predictors of response to anterior cingulotomy for obsessive compulsive disorder.作为强迫症患者前扣带回切开术反应潜在预测指标的脑代谢相关性
Biol Psychiatry. 2001 Nov 1;50(9):659-67. doi: 10.1016/s0006-3223(01)01188-x.
3
Stereotactic cingulotomy.立体定向扣带回毁损术。
Neurosurg Clin N Am. 2003 Apr;14(2):225-35. doi: 10.1016/s1042-3680(02)00115-8.
4
Dorsal anterior cingulotomy and anterior capsulotomy for severe, refractory obsessive-compulsive disorder: a systematic review of observational studies.用于治疗重度难治性强迫症的背侧前扣带回切开术和前囊切开术:观察性研究的系统评价
J Neurosurg. 2016 Jan;124(1):77-89. doi: 10.3171/2015.1.JNS14681. Epub 2015 Aug 7.
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Comment on the study 'Long-term efficacy of stereotactic bilateral anterior cingulotomy and bilateral anterior capsulotomy as a treatment for refractory obsessive-compulsive disorder' by Zhang et al.对张等人所著的《立体定向双侧前扣带回切开术和双侧内囊前肢切开术治疗难治性强迫症的长期疗效》研究的评论
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Bilateral anterior cingulotomy for refractory obsessive-compulsive disorder: Long-term follow-up results.双侧前扣带回切开术治疗难治性强迫症:长期随访结果。
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Long-term efficacy of stereotactic bilateral anterior cingulotomy and bilateral anterior capsulotomy as a treatment for refractory obsessive-compulsive disorder.立体定向双侧扣带回切开术和双侧内囊前肢切开术治疗难治性强迫症的长期疗效
Stereotact Funct Neurosurg. 2013;91(4):258-61. doi: 10.1159/000348275. Epub 2013 May 7.
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Lesion location and outcome following cingulotomy for obsessive-compulsive disorder.扣带回切开术治疗强迫症的病灶位置与结果。
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Neuroanatomical characteristics associated with response to dorsal anterior cingulotomy for obsessive-compulsive disorder.与强迫症患者接受背侧前扣带回切开术反应相关的神经解剖学特征。
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Metabolic imaging of bilateral anterior capsulotomy in refractory obsessive compulsive disorder: an FDG PET study.双侧额前扣带回切开术治疗难治性强迫症的代谢成像:一项 FDG PET 研究。
J Cereb Blood Flow Metab. 2013 Jun;33(6):880-7. doi: 10.1038/jcbfm.2013.23. Epub 2013 Feb 27.

引用本文的文献

1
Brain perfusion single photon emission computed tomography in major psychiatric disorders: From basics to clinical practice.主要精神障碍中的脑灌注单光子发射计算机断层扫描:从基础到临床实践
Indian J Nucl Med. 2014 Oct;29(4):210-21. doi: 10.4103/0972-3919.142622.
2
Surgical treatment of obsessive compulsive disorders: Current status.强迫症的外科治疗:现状
Indian J Psychiatry. 2009 Jul-Sep;51(3):216-21. doi: 10.4103/0019-5545.55095.
3
An emerging role for escitalopram in the treatment of obsessive-compulsive disorder.艾司西酞普兰在强迫症治疗中的新作用。
Neuropsychiatr Dis Treat. 2007 Aug;3(4):455-61.