Talbot Laura A, Gaines Jean M, Ling Shari M, Metter E Jeffrey
The Johns Hopkins University, School of Nursing, Baltimore, Maryland 21205-2110, USA.
J Rheumatol. 2003 Jul;30(7):1571-8.
To determine whether home-based neuromuscular electrical stimulation (NMES) applied to the quadriceps femoris (QF) muscle increases strength, physical activity, and physical performance in older adults with knee osteoarthritis (OA).
Thirty-four adults (> 60 yrs) with radiographically confirmed symptomatic knee OA were randomized to NMES plus education or education only (EDU). The primary outcome was isometric QF peak torque (PTIso), with secondary outcomes of daily step counts, total activity vector magnitude, 100-foot walk-turn-walk, timed stair climb, chair rise, and pain. The NMES group used a portable electrical muscle stimulator 3 days a week for unilateral QF training with incremental increases in the intensity of isometric contraction to 30-40% of maximum over 12 weeks. Both groups received the 12-week Arthritis Self-Management course and were followed an additional 12 weeks.
The stimulated knee-extensor showed a 9.1% increase in 120 degrees PTIso compared to a 7% loss in the EDU group (time x group interaction for 120 degrees PTIso; p = 0.04). The chair rise time decreased by 11% in the NMES group, whereas the EDU group saw a 7% reduction (p = 0.01, time; p = 0.9, group). Similarly, both groups improved their walk time by approximately 7% (p = 0.02, time; p = 0.61 group). Severity of pain reported following intervention did not differ between groups.
In older adults with knee OA, a home-based NMES protocol appears to be a promising therapy for increasing QF strength in adults with knee OA without exacerbating painful symptoms.
确定对股四头肌(QF)进行居家神经肌肉电刺激(NMES)是否能增强膝关节骨关节炎(OA)老年患者的力量、身体活动能力和身体表现。
34名经影像学证实患有症状性膝关节OA的成年人(年龄>60岁)被随机分为NMES加教育组或仅接受教育组(EDU)。主要结局指标是等长股四头肌峰值扭矩(PTIso),次要结局指标包括每日步数、总活动向量大小、100英尺步行转身步行、定时爬楼梯、从椅子上起身以及疼痛情况。NMES组每周使用便携式肌肉电刺激器3天,对单侧股四头肌进行训练,在12周内将等长收缩强度逐渐增加至最大值的30 - 40%。两组均接受为期12周的关节炎自我管理课程,并额外随访12周。
与EDU组7%的下降相比,接受刺激的膝关节伸肌在120度时的PTIso增加了9.1%(120度PTIso的时间×组间交互作用;p = 0.04)。NMES组从椅子上起身的时间减少了11%,而EDU组减少了7%(p = 0.01,时间;p = 0.9,组间)。同样,两组的步行时间均改善了约7%(p = 0.02,时间;p = 0.61,组间)。干预后两组报告的疼痛严重程度无差异。
对于患有膝关节OA的老年人,居家NMES方案似乎是一种有前景的治疗方法,可增强膝关节OA成年人的股四头肌力量,且不会加剧疼痛症状。