Kahl Ulrika
Institutionen för medicinsk epidemiologi och biostatistik, Karolinska institutet, Stockholm.
Lakartidningen. 2003 Jun 19;100(25):2218-21.
It is now 50 years since the double helical structure of DNA was discovered. Even if the knowledge about the DNA structure has had great implications for many disciplines in medical and genetic research, the big breakthrough is still to come in clinical practice. Much research is now focusing on elucidating the regulatory mechanisms controlling the activity and behaviour of the genes of our genome. Many researchers and clinicians are hoping that the tangle of nucleic acids and proteins that fills the cellular nucleus harbours interesting and potential drug targets.