Hoshikawa Hiroshi, Goto Rieko, Karaki Masayuki, Miyabe Kazunori, Mori Nozomu
Department of Otolaryngology, Kagawa Medical University, Kagawa.
Nihon Jibiinkoka Gakkai Kaiho. 2003 Jun;106(6):700-4. doi: 10.3950/jibiinkoka.106.700.
Subjects were 51 patients undergoing folded pharyngeal flap surgery for velopharyngeal incompetence at the Department of Otolaryngology of Kagawa Medical University between August 1985 and July 2001. Causal diseases were cleft palate in 27 (53%), submucous cleft palate in 8 (16%), and congenital velopharyngeal incompetence in 16 (31%). In history, 31% with congenital velopharyngeal incompetence, 25% with submucous cleft palate, and 11% with cleft palate had congenital abnormalities. In addition, 56% with congenital velopharyngeal incompetence, 38% with submucous cleft palate, and 15% with cleft palate had mental retardation, indicating that it occurred with high frequency in patients with congenital velopharyngeal incompetence. The postoperative improvement of nasality was investigated in 48 patients whose progress could be observed for more than 1 year. Of 39 preoperatively diagnosed with advanced velopharyngeal dysfunction, 34 (87%) showed improved nasality. Of 9 with preoperatively slight deficiency, 8 (89%) improved nasality. The blowing test showed no difference in results between patients who had advanced and slight deficiency. Articulation on speech level improved to be normal in 78% of patients with slight deficiency, but only in 46% of those with advanced deficiency. Improvement of articulation on a speech level was high (86%) in patients with submucous cleft palate, but low in patients with congenital velopharyngeal incompetence who had mental retardation. Further study is required to detail postoperative prognosis factors.
研究对象为1985年8月至2001年7月期间在香川医科大学耳鼻咽喉科接受折叠咽瓣手术治疗腭咽闭合不全的51例患者。病因疾病中,腭裂27例(53%),黏膜下腭裂8例(16%),先天性腭咽闭合不全16例(31%)。在病史方面,先天性腭咽闭合不全患者中有31%、黏膜下腭裂患者中有25%、腭裂患者中有11%存在先天性异常。此外,先天性腭咽闭合不全患者中有56%、黏膜下腭裂患者中有38%、腭裂患者中有15%存在智力发育迟缓,表明其在先天性腭咽闭合不全患者中发生率较高。对48例病程可观察1年以上的患者术后鼻音改善情况进行了调查。术前诊断为重度腭咽功能障碍的39例患者中,34例(87%)鼻音改善。术前轻度腭咽功能不全的9例患者中,8例(89%)鼻音改善。吹气试验结果显示,重度和轻度腭咽功能不全患者之间无差异。轻度腭咽功能不全患者中78%的言语清晰度改善至正常,但重度腭咽功能不全患者中仅46%改善。黏膜下腭裂患者言语清晰度改善率较高(86%),但伴有智力发育迟缓的先天性腭咽闭合不全患者言语清晰度改善率较低。需要进一步研究以详细了解术后预后因素。