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肌肉收缩及相关溶液系统中的自由能水平与熵产生

Free energy levels and entropy production in muscle contraction and in related solution systems.

作者信息

Hill T L, Simmons R M

出版信息

Proc Natl Acad Sci U S A. 1976 Feb;73(2):336-40. doi: 10.1073/pnas.73.2.336.

Abstract

"Basic" and "gross" free energy levels of a macromolecule such as myosin or Na,K-ATPase, defined in a previous publication, are discussed here for two relatively complicated cases: a six-state kinetic diagram of the sort that could be used to describe the actin activation of myosin-ATPase in solution; and muscle contraction, where a similar kinetic diagram is needed for each value of a positional variable X.

摘要

本文讨论了先前出版物中定义的诸如肌球蛋白或钠钾ATP酶等大分子的“基本”和“总”自由能水平,涉及两种相对复杂的情况:一种可用于描述溶液中肌球蛋白-ATP酶的肌动蛋白激活的六态动力学图;以及肌肉收缩,其中对于位置变量X的每个值都需要类似的动力学图。

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