Bernhardt T M, Krause U W, Philipp C, Allhoff E P, Rapp-Bernhardt U
Institut für Klinische Radiologie, Universität Münster, Münster.
Rofo. 2003 Aug;175(8):1106-11. doi: 10.1055/s-2003-40918.
Virtual cystoscopy at different mAs settings in patients with tumors of the bladder in comparison with cystoscopy and axial CT.
The study included 28 patients with bladder tumors and 28 patients without tumors as control group. The bladder was distended with air and scanned at two different mAs settings (protocol 1 and 2). The radiation exposure was reduced by 82 % for protocol 2 in comparison with protocol 1. Three readers compared virtual cystoscopy with cystoscopy and axial CT as to tumor location and size. Sensitivity, specificity and accuracy were calculated.
Of the 47 tumors seen at cystoscopy, all readers detected 45 tumors by virtual cystoscopy using protocol 1 and 44 tumors using protocol 2, with p > 0.05 in comparison with cystoscopy. Virtual cystoscopy showed higher sensitivity than axial CT (97.2 % vs. 86.5 % for protocol 1) and (96.5 % vs. 86.5 % for protocol 2) with the same specificity (100 %). The accuracy was 0.982 for protocol 1 and 0.978 for protocol 2. In comparison with virtual cystoscopy, axial CT shoved more often over- and underestimation of the tumor size.
Virtual cystoscopy at reduced mAs setting is a modality suitable for the detection of polypoid tumors, but does not provide data of the mucosa and thus cannot replace cystoscopy yet.
比较不同毫安秒（mAs）设置下的虚拟膀胱镜检查与膀胱镜检查及轴向CT在膀胱肿瘤患者中的应用。
该研究纳入28例膀胱肿瘤患者和28例无肿瘤患者作为对照组。膀胱充气后在两种不同的mAs设置下（方案1和方案2）进行扫描。与方案1相比，方案2的辐射暴露减少了82%。三位阅片者将虚拟膀胱镜检查与膀胱镜检查及轴向CT在肿瘤位置和大小方面进行比较。计算敏感性、特异性和准确性。
在膀胱镜检查中发现的47个肿瘤中，所有阅片者通过方案1的虚拟膀胱镜检查检测到45个肿瘤，通过方案2检测到44个肿瘤，与膀胱镜检查相比，p>0.05。虚拟膀胱镜检查显示出比轴向CT更高的敏感性（方案1为97.2%对86.5%）和（方案2为96.5%对86.5%），特异性相同（100%）。方案1的准确性为0.982，方案2的准确性为0.978。与虚拟膀胱镜检查相比，轴向CT更常出现对肿瘤大小的高估和低估。
在降低mAs设置下的虚拟膀胱镜检查是一种适用于检测息肉样肿瘤的方法，但不能提供黏膜数据，因此尚不能替代膀胱镜检查。
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