Lautrette A, Merrer J, Murgue B
Service de néphrologie A, Hôpital Tenon, Paris.
Nephrologie. 2003;24(4):167-71.
Hantavirus infections, Puumala serotype, is a well-known disease in the northeast of France, but not in the Paris area, despite regularly diagnosed cases. A retrospective study was performed from January 1999 to December 2000 to assess the clinical and epidemiological characteristics of this disease in the "Région Ile-de-France". Fourteen cases were diagnosed. All required hospitalisation. Patients presented usually with high fever, pain, renal failure, moderate thrombocytopenia and, sometimes, transitional acute myopia witch is pathognomonic of the disease. In each case, a contact with a forest was found. Twelve patients recovered completely. One patient with pre-existing chronic renal and hepatic failure died and another developed a persistent arterial hypertension. Invasive procedures were often used before the diagnosis. Hantavirus infections does exist in the "Région Ile-de-France". Failure to recognise this disease in this area lead to unnecessary invasive procedures and hospitalizations.
普马拉血清型汉坦病毒感染在法国东北部是一种众所周知的疾病,但在巴黎地区并非如此,尽管时有确诊病例。1999年1月至2000年12月进行了一项回顾性研究,以评估法兰西岛大区该疾病的临床和流行病学特征。共诊断出14例病例。所有患者均需住院治疗。患者通常表现为高热、疼痛、肾衰竭、中度血小板减少,有时还会出现具有该疾病特征性的一过性急性近视。在每例病例中,均发现与森林有过接触。12名患者完全康复。1例原有慢性肾衰竭和肝衰竭的患者死亡,另1例出现持续性动脉高血压。在诊断前常采用侵入性操作。法兰西岛大区确实存在汉坦病毒感染。在该地区未能识别这种疾病会导致不必要的侵入性操作和住院治疗。