爬行动物中的肌苷酸-鸟苷酸5'-核苷酸酶：在一只乌龟、一只陆龟和三种蛇类中的存在情况。

IMP-GMP 5'-nucleotidase in reptiles: occurrence in a turtle, a tortoise and three species of snakes.

作者信息

Itoh Roichi, Kimura Kayoko

机构信息

Department of Home Economics, Tokyo Kasei Gakuin University, 2600 Aiharamachi, Machida-city, Tokyo 194-0292, Japan.

出版信息

Comp Biochem Physiol B Biochem Mol Biol. 2003 Aug;135(4):657-62. doi: 10.1016/s1096-4959(03)00147-7.

DOI:10.1016/s1096-4959(03)00147-7

PMID:12892757

Abstract

IMP-hydrolyzing activity, which is reactive with goose anti-pig lung IMP-GMP 5'-nucleotidase (c-N-II: EC.3.1.3.5) serum, was detected in extracts from liver, heart, kidney, spleen, stomach, skeletal muscle and lung from several species of reptiles: The values found in liver (U/mg protein) of one animal were: 4.5 for an ammono-ureotelic turtle (Trionyx sinensis japonicus); 3.7 for an ureo-uricotelic tortoise (Testudo elegans); 13-23 for three species of uricotelic snakes: Elaphe quadrivirgata, Elaphe conspicillata and Elaphe climacophora. These findings suggest that in the liver of snakes, c-N-II may participate in the production of uric acid as an end product of amino acid metabolism.

摘要

在几种爬行动物的肝脏、心脏、肾脏、脾脏、胃、骨骼肌和肺的提取物中检测到了与鹅抗猪肺肌苷酸 - 鸟苷酸5'-核苷酸酶（c-N-II：EC.3.1.3.5）血清反应的肌苷酸水解活性：一只动物肝脏中的数值（单位：U/mg蛋白质）如下：中华鳖（Trionyx sinensis japonicus），一种氨 - 尿素排泄型龟，为4.5；缅甸陆龟（Testudo elegans），一种尿素 - 尿酸排泄型陆龟，为3.7；三种尿酸排泄型蛇：四线锦蛇（Elaphe quadrivirgata）、玉斑锦蛇（Elaphe conspicillata）和日本锦蛇（Elaphe climacophora），为13 - 23。这些发现表明，在蛇的肝脏中，c-N-II可能作为氨基酸代谢的终产物参与尿酸的产生。