意大利博洛尼亚人群中三个高变线粒体DNA区域的不同信息性
Different informativeness of the three hypervariable mitochondrial DNA regions in the population of Bologna (Italy).
作者信息
Bini C, Ceccardi S, Luiselli D, Ferri G, Pelotti S, Colalongo C, Falconi M, Pappalardo G
机构信息
Department of Medicine and Public Health, Section of Legal Medicine, University of Bologna, via Irnerio 49, 40126 Bologna, Italy.
出版信息
Forensic Sci Int. 2003 Jul 29;135(1):48-52. doi: 10.1016/s0379-0738(03)00167-1.
Mitochondrial DNA (mtDNA) sequence variations at hypervariable regions HVI, HVII and HVIII were analysed in 100 unrelated Italians from Bologna. The values of the statistical parameters are in agreement with the range of European populations. We suggest that the less informative HVIII region may be useful to distinguish HVI-HVII identical sequences in forensic analysis especially when nuclear DNA cannot be investigated.
对来自博洛尼亚的100名无亲缘关系的意大利人的线粒体DNA（mtDNA）高变区HVI、HVII和HVIII的序列变异进行了分析。统计参数值与欧洲人群的范围一致。我们认为，信息量较少的HVIII区域可能有助于在法医分析中区分HVI - HVII相同序列，特别是在无法检测核DNA时。
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