紫精相关化合物对DNA的切割及其掺入寡脱氧核糖核苷酸中。
Cleavage of DNA by viologen related compounds and their incorporation into oligodeoxyribonucleotides.
作者信息
Ikeda H, Tanaka K, Fuji K
机构信息
Institute for Chemical Research, Kyoto University, Japan.
出版信息
Nucleic Acids Symp Ser. 1992(27):5-6.
PMID:1289823
Abstract
The DNA cleavage reaction by viologen and related compound such as 2,7-diazapyrenium salt was investigated. These viologen analogues were successfully incorporated into the oligothymidylate in the form of covalent bonding at the site of the phosphorous backbone through the linker arm.
摘要
研究了紫精及相关化合物（如2,7-二氮杂芘盐）的DNA切割反应。这些紫精类似物通过连接臂以共价键的形式成功地掺入到磷主链位点的寡聚胸苷酸中。
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