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[腹腔镜肾上腺切除术治疗肾上腺恶性病变]

[Laparoscopic adrenalectomy in the treatment of malignant adrenal lesions].

作者信息

Lombardi C P, Raffaelli M, Boscherini M, De Crea C, Alesina P F, Traini E, Princi P, Bellantone R

机构信息

Divisione di Endocrinochirurgia, Università Cattolica del Sacro Cuore, Roma.

出版信息

Tumori. 2003 Jul-Aug;89(4 Suppl):255-6.

Abstract

The role of laparoscopic approach for the treatment of malignant adrenal diseases is still controversial. The aim of this study was to verify the results of laparoscopic adrenalectomy in the management of adrenal malignancies. The medical records of all the patients who underwent laparoscopic procedures for adrenal diseases and in whom malignancy was demonstrated at final histology were reviewed. Nine patients were included (3 malignant pheochromocytomas, 4 adrenocortical carcinomas and 2 adrenal metastases). At a mean follow-up of 17.0 +/- 12.8 months (range, 2-36), all but two patients were alive and disease free. One patient died for unrelated causes. No patient developed local or port site recurrence. The results of this study demonstrate that laparoscopic adrenalectomy can be safe and effective also in case of adrenal malignancies. Conversion to open surgery in mandatory in case of local invasion and when the dissection cannot be as accurate as in conventional operations. A preliminary laparoscopic exploration can be planned in case of suspected malignant lesions to confirm the diagnosis and to evaluate their operability.

摘要

腹腔镜手术治疗肾上腺恶性疾病的作用仍存在争议。本研究的目的是验证腹腔镜肾上腺切除术治疗肾上腺恶性肿瘤的效果。回顾了所有接受肾上腺疾病腹腔镜手术且最终病理证实为恶性肿瘤患者的病历。共纳入9例患者(3例恶性嗜铬细胞瘤、4例肾上腺皮质癌和2例肾上腺转移瘤)。平均随访17.0±12.8个月(范围2 - 36个月),除2例患者外,其余患者均存活且无疾病复发。1例患者死于无关原因。无患者出现局部或切口部位复发。本研究结果表明,腹腔镜肾上腺切除术在肾上腺恶性肿瘤的治疗中也可安全有效。若出现局部侵犯或手术分离无法像传统手术那样精确时,则必须转为开放手术。对于疑似恶性病变,可计划进行初步腹腔镜探查以确诊并评估其可切除性。

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