Woo Jean, Lau Edith, Lau Chak Sing, Lee Polly, Zhang James, Kwok Timothy, Chan Cynthia, Chiu P, Chan Kai Ming, Chan A, Lam D
The Chinese University of Hong Kong, Hong Kong.
Arthritis Rheum. 2003 Aug 15;49(4):526-34. doi: 10.1002/art.11198.
To determine the direct and indirect cost of osteoarthritis (OA) according to disease severity, and to estimate the total cost of the disease in Hong Kong.
This study is a retrospective, cross-sectional, nonrandom, cohort design, with subjects stratified according to disease severity based on functional limitation and the presence or absence of joint prosthesis. Subjects were recruited from primary care, geriatric medicine, rheumatology, and orthopedic clinics. There were 219 patients in the mild disease category, 290 patients in the severe category, and 65 patients with joint replacement. A questionnaire gathered information on demographic and socioeconomic characteristics, function limitation, use of health and social services, and effect on occupation and living arrangements over the previous 12 months. Costs were calculated as direct and indirect.
Low education and socioeconomic class were associated with more severe disease. OA affected family or close relationships in 44%. The average cost incurred as a result of side effects of medication is similar to the average cost of medication itself. Excluding joint replacement, the direct costs ranged from Hong Kong (HK) dollar $11,690 to $40,180 per person per year and indirect costs, HK $3,300-$6,640. The direct costs are comparable to those reported in Western countries; however, the ratio of direct to indirect costs is much higher than 1, in contrast to the greater indirect versus direct costs reported in whites. The total cost expressed as a percentage of gross national product is also much lower in Hong Kong.
The socioeconomic impact of OA in the Hong Kong population is comparable to Western countries, but the economic burden is largely placed on the government, with patients having relatively low out-of-pocket expenditures.
根据疾病严重程度确定骨关节炎(OA)的直接和间接成本,并估算香港该疾病的总成本。
本研究采用回顾性、横断面、非随机队列设计,根据功能受限情况以及是否存在关节假体,将受试者按疾病严重程度分层。受试者从基层医疗、老年医学、风湿病学和骨科诊所招募。轻度疾病组有219例患者,重度疾病组有290例患者,关节置换组有65例患者。通过问卷调查收集了有关人口统计学和社会经济特征、功能受限、健康和社会服务使用情况以及过去12个月对职业和生活安排影响的信息。成本分为直接成本和间接成本进行计算。
低教育水平和社会经济阶层与更严重的疾病相关。44%的OA患者表示该病影响了家庭或亲密关系。药物副作用产生的平均成本与药物本身的平均成本相似。不包括关节置换,直接成本为每人每年11,690至40,180港元,间接成本为3,300至6,640港元。直接成本与西方国家报告的成本相当;然而,直接成本与间接成本之比远高于1,这与白人中报告的间接成本高于直接成本形成对比。以占国民生产总值的百分比表示的总成本在香港也低得多。
香港人群中OA的社会经济影响与西方国家相当,但经济负担主要由政府承担,患者自付费用相对较低。