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仅使用原位动脉血管进行非体外循环冠状动脉旁路移植术以实现完全血运重建,能做到何种程度?

[How much can off-pump coronary artery bypass grafting be performed for complete revascularization using only in situ arterial conduits?].

作者信息

Niinami H, Takeuchi Y, Suda Y, Tabata M, Yamamoto M, Asano R, Ikeda M

机构信息

Department of Cardiovascular Surgery, Daini Hospital, Tokyo Women's Medical University, Tokyo, Japan.

出版信息

Kyobu Geka. 2003 Jul;56(8 Suppl):661-6.

Abstract

With the rapid advance of percutaneous catheter intervention, the direction taken by surgeons is not only to make coronary artery bypass grafting (CABG) less invasive but also to obtain better long-term results by using more arterial conduits. However, off-pump CABG (OPCAB) with only in situ arterial conduits such as the left and right internal thoracic arteries (ITAs) and the right gastroepiploic artery (RGEA) is technically demanding for the surgeon. The purpose of this study was to demonstrate the feasibility and safety of this technique. From January 2002 to December 2002, 57 patients underwent isolated CABG without cardiopulmonary bypass, excluding minimally invasive direct coronary artery bypass (MIDCAB) cases. There were 44 men and 13 women with a mean age of 64.1 years. Most of the patients (95%) underwent postoperative angiography within 1 month after surgery. The mean number of anastomoses was 3.8 +/- 1.4 (range 2-8). One patient suffered from mediastinitis and another from stroke. All patients were discharged from the hospital. Fifty patients (88%) received only in situ grafts for complete revascularization. Forty-one patients received bilateral ITAs and 27 received bilateral ITAs and RGEA. The mean number of anastomoses using bilateral ITAs and RGEA was 4.5 +/- 1.2 (range 3-8). The patency rate was 98%. Complete arterial revascularization with only in situ arterial conduits was associated with minimal operative risk and a high early graft patency rate, even in the off-pump situation. These results indicate that complete revascularization can be achieved in OPCAB with the exclusive use of in situ arterial conduits in patients with diffuse coronary arterial disease.

摘要

随着经皮导管介入技术的迅速发展,外科医生的方向不仅是使冠状动脉旁路移植术(CABG)的侵入性更小,而且要通过使用更多的动脉移植物获得更好的长期效果。然而,仅使用原位动脉移植物(如左、右胸廓内动脉(ITA)和右胃网膜动脉(RGEA))的非体外循环冠状动脉旁路移植术(OPCAB)对外科医生来说技术要求很高。本研究的目的是证明该技术的可行性和安全性。2002年1月至2002年12月,57例患者接受了非体外循环下的单纯冠状动脉旁路移植术,不包括微创直接冠状动脉旁路移植术(MIDCAB)病例。其中男性44例,女性13例,平均年龄64.1岁。大多数患者(95%)在术后1个月内接受了血管造影。平均吻合口数量为3.8±1.4(范围2 - 8)。1例患者发生纵隔炎,另1例发生中风。所有患者均出院。50例患者(88%)仅接受原位移植物进行完全血运重建。41例患者接受双侧胸廓内动脉,27例患者接受双侧胸廓内动脉和右胃网膜动脉。使用双侧胸廓内动脉和右胃网膜动脉的平均吻合口数量为4.5±1.2(范围3 - 8)。通畅率为98%。即使在非体外循环情况下,仅使用原位动脉移植物进行完全动脉血运重建的手术风险最小,早期移植物通畅率高。这些结果表明,对于弥漫性冠状动脉疾病患者,在非体外循环冠状动脉旁路移植术中仅使用原位动脉移植物可实现完全血运重建。

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