First synthesis of 2',3'-epimino-carbocyclic nucleosides.
作者信息
Ishikura Minoru, Murakami Atsushi, Katagiri Nobuya
机构信息
Faculty of Pharmaceutical Sciences, Health Sciences University of Hokkaido, Ishikari-Tobetsu, Hokkaido 061-0293, Japan.
出版信息
Org Biomol Chem. 2003 Feb 7;1(3):452-3. doi: 10.1039/b210963h.
DOI:10.1039/b210963h
PMID:12926242
Abstract
The preparation of 2',3'-epimino-carbocyclic analogues of adenosine is reported. The reaction of p-tosyl azide with N-substituted 2-azabicyclo[2.2.1]hept-5-en-3-one (ABH) (1a) provided aziridine-fused ABH (2), which was converted to 2',3'-epimino-carbocyclic nucleosides (11).
摘要
Zotero 插件