Ammar Jamel, Ghrairi Hédia, el Mekki Fathi, Aissa Imen, Hamzaoui Agnés
Service de pneumologie, Pavillon B. Hopital Abderrahmen Mami, Ariana, Tunisie.
Tunis Med. 2003 May;81(5):345-50.
The Acute Chest Syndrome is a frequent complication of sickle cell disease characterised by chest pain, fever and new infiltrate on chest X ray image. Early diagnosis and treatment are needed for Acute Chest Syndrome, which the aetiology remains unknown on more than half of cases. We report 3 cases of Acute Chest Syndrome with different aetiology due to a fat embolism in the first case, a pleuro-pneumonia infection in the second case and to tuberculosis in the third case. This report illustrates the importance of the bronchoscopy and the brochoalveolar lavage in the determination of the aetiology of Acute Chest Syndrome allowing to isolate microbial agents in pulmonary infections or fatty macrophages in fat embolism.
急性胸综合征是镰状细胞病的常见并发症，其特征为胸痛、发热以及胸部X光影像上新出现的浸润影。急性胸综合征需要早期诊断和治疗，在超过半数的病例中其病因仍不明。我们报告3例急性胸综合征，病因各不相同，第一例为脂肪栓塞，第二例为胸膜肺炎感染，第三例为肺结核。本报告说明了支气管镜检查和支气管肺泡灌洗在确定急性胸综合征病因方面的重要性，这有助于分离出肺部感染中的微生物病原体或脂肪栓塞中的脂肪巨噬细胞。
