Osugi Harushi, Lee Shigeru, Takemura Masashi, Higashino Masayuki
Department of Gastroenterological Surgery, Osaka City University, Graduate School of Medicine, Osaka, Japan.
Nihon Geka Gakkai Zasshi. 2003 Aug;104(8):544-8.
Intraesophageal stenting using a self-expandable metallic stent is currently the first choice for patients with unresectable malignant stricture of the esophagus to improve their quality of life because of its efficacy and less invasiveness. Two types of stent are commercially available in Japan. The Ultraflex stent (Boston Scientific Co. Ltd.) is more flexible and less expandable than the Cook-Z stent (Wilson-Cook Co. Ltd.). Care should be taken based on the position of the stricture. Stenting in the cervical esophagus may cause discomfort. Stenting for a lesion adjacent to the airway may cause airway obstruction. Therefore airway stenting or provision for emergency intratracheal intubation is necessary. A stent with an antireflux mechanism would be effective in preventing gastroesophageal reflux following stenting at the esophagogastric junction. The development and legal approval of a stent with antireflux mechanism are expected. Some reported that anticancer treatment after stenting was effective, and some radiologists cautioned against the risk of radiation after stenting. The safety and efficacy of anticancer treatment after stenting remain to be clarified.
对于无法切除的食管恶性狭窄患者,使用自膨式金属支架进行食管内支架置入术因其疗效显著且侵入性较小,目前是改善患者生活质量的首选方法。在日本有两种支架可供商业使用。与库克 - Z支架(威尔逊 - 库克公司)相比,超弹性支架(波士顿科学有限公司)更具柔韧性但扩张性较小。应根据狭窄的位置谨慎操作。在颈段食管置入支架可能会引起不适。在气道附近的病变处置入支架可能会导致气道阻塞。因此,气道支架置入或紧急气管插管准备是必要的。具有抗反流机制的支架对于预防食管胃交界处支架置入术后的胃食管反流是有效的。人们期待具有抗反流机制的支架的研发和获得法律批准。一些人报道支架置入术后的抗癌治疗是有效的,而一些放射科医生则对支架置入术后的辐射风险提出了警告。支架置入术后抗癌治疗的安全性和有效性仍有待阐明。