一只幼犬的胃肠道隐孢子虫病。

Gastrointestinal cryptosporidiosis in a puppy.

作者信息

Miller D L, Liggett A, Radi Z A, Branch L O

机构信息

The University of Georgia, College of Veterinary Medicine, Veterinary Diagnostic and Investigational Laboratory, Tifton, GA 31793, USA.

出版信息

Vet Parasitol. 2003 Jul 29;115(3):199-204. doi: 10.1016/s0304-4017(03)00237-1.

DOI:10.1016/s0304-4017(03)00237-1

PMID:12935734

Abstract

An 8-week-old female Yorkshire terrier with a history of weakness, diarrhea and intestinal isosporiasis was euthanized and a post mortem examination performed. Histologically, there was severe gastrointestinal cryptosporidiosis, severe intestinal isosporiasis and thymic lymphoid depletion. PCR revealed visible bands for the actin and 18S rRNA genes but not for the acetyl CoA synthetase gene for Cryptosporidium spp. The PCR product for the actin gene was sequenced and found to have a 97.6-99.8% similarity to that of Cryptosporidium canis. To our knowledge, this is the first report of gastric cryptosporidiosis in a canine.

摘要

一只8周龄雌性约克夏梗犬，有虚弱、腹泻和肠道等孢球虫病病史，实施安乐死后进行了尸检。组织学检查发现有严重的胃肠道隐孢子虫病、严重的肠道等孢球虫病和胸腺淋巴细胞耗竭。聚合酶链反应（PCR）显示肌动蛋白和18S核糖体RNA基因有可见条带，但隐孢子虫属的乙酰辅酶A合成酶基因无条带。对肌动蛋白基因的PCR产物进行测序，发现与犬隐孢子虫的相似性为97.6% - 99.8%。据我们所知，这是犬胃隐孢子虫病的首例报告。