孕期抗癫痫药物：对儿童认知能力的远期影响。初步数据。

Antiepileptic drugs in pregnancy: late effects on the children's cognitive abilities. Preliminary data.

作者信息

Perniola T, Buttiglione M, Margari L

机构信息

Neurological Clinic, University of Bari, Italy.

出版信息

Acta Neurol (Napoli). 1992 Aug-Dec;14(4-6):543-6.

PMID:1293996

Abstract

The authors report preliminary data on cognitive development of 57 children, perspectively followed, who were exposed to antiepileptic drugs in utero for maternal epilepsy. Cognitive impairments are associated with other risk factors in 5 cases, so that a direct AEDs responsibility is not easy to prove.

摘要

作者报告了57名儿童认知发展的初步数据，这些儿童因母亲患有癫痫而在子宫内接触了抗癫痫药物，并对其进行了前瞻性跟踪。5例中认知障碍与其他风险因素有关，因此难以直接证明抗癫痫药物的责任。