Bühling K J, Dudenhausen J W
Klinik für Geburtsmedizin, Charité Campus Virchow-Klinikum, Berlin.
Zentralbl Gynakol. 2003 Mar-Apr;125(3-4):123-8. doi: 10.1055/s-2003-41868.
In Germany, the diagnosis of gestational diabetes is recognized in only 10% of the patients with gestational diabetes. Therefore 36,000 pregnant patients per year are undiagnosed. The reason is an insufficient screening system which plans only the determination of the glucosuria at each prenatal visit. Several studies have shown the low sensitivity of glucosuria in the detection of gestational diabetes. The majority of the gynecologists are under the assumption of having a healthy pregnant woman in front of them. Therefore a screening with the 50 g-glucose screening test or the 75 g-oral glucose tolerance test is necessary. Our observations have shown an influence of the previous meal on the 50 g-glucose screening test. Therefore we would prefer the one-step screening with the 75 g-oral glucose test. The costs of the one-step or two-step regimen are similar. Also a screening only of high risk pregnancies appears insufficient. Using an average age below 25 years and body-mass index below 25 kg/mg2, only 13.7% of our patients would not be screened. Of those, 3.1% have gestational diabetes. The decision to offer the screening as an individual health achievement, which has to be paid by the patients, does not take into consideration the importance of the illness. A general screening, preferably one-step screening should be offered to each pregnant woman.
在德国,仅10%的妊娠期糖尿病患者能得到确诊。因此,每年有36000名孕妇未被诊断出患有该病。原因是筛查系统不完善,仅计划在每次产前检查时测定尿糖。多项研究表明,尿糖检测妊娠期糖尿病的敏感性较低。大多数妇科医生认为面前的孕妇是健康的。因此,进行50克葡萄糖筛查试验或75克口服葡萄糖耐量试验是必要的。我们的观察表明,前一餐会对50克葡萄糖筛查试验产生影响。因此,我们更倾向于采用75克口服葡萄糖试验进行一步筛查。一步法或两步法方案的成本相似。仅对高危妊娠进行筛查似乎也不够。以平均年龄低于25岁且体重指数低于25kg/m²计算,我们的患者中只有13.7%不会接受筛查。其中,3.1%患有妊娠期糖尿病。将筛查作为一项需患者付费的个人健康项目的决定,没有考虑到该疾病的重要性。应向每位孕妇提供常规筛查,最好是一步筛查。