马来西亚城市地区献血者和发热患者中恙虫病东方体、斑疹伤寒立克次体及TT118斑点热群立克次体的抗体流行情况。

Antibody prevalence of Orientia tsutsugamushi, Rickettsia typhi and TT118 spotted fever group rickettsiae among Malaysian blood donors and febrile patients in the urban areas.

作者信息

Tay S T, Kamalanathan M, Rohani M Y

机构信息

Department of Medical Microbiology, Faculty of Medicine, University of Malaya, Malaysia.

出版信息

Southeast Asian J Trop Med Public Health. 2003 Mar;34(1):165-70.

PMID:12971530

Abstract

The seroprevalence of Orientia tsutsugamushi (OT), Rickettsia typhi (RT) and TT118 spotted fever group rickettsiae (SFGR) among blood donors and febrile Malaysian patients in the urban areas was determined. Of the 240 blood donors, 5.4%, 9.2% and 1.7% had either present or previous exposure to OT, RT and SFG rickettsiae, respectively. Patients admitted to an urban hospital had high seroprevalences of OT (43.5%) and RT (22.9%), as compared to SFGR (11.6%). Antibody levels suggestive of recent infections of scrub typhus, murine typhus and tick typhus were detected in 16.8%, 12.7% and 8.2% of patients respectively. No significant difference was noted in the distribution of rickettsial antibodies among urban patients from 2 geographical locations. However, the serologic patterns of rickettsial infection in the urban areas were different form those of rural areas.

摘要

对马来西亚城市地区献血者和发热患者中恙虫病东方体（OT）、伤寒立克次体（RT）和TT118斑点热群立克次体（SFGR）的血清流行率进行了测定。在240名献血者中，分别有5.4%、9.2%和1.7%曾感染或既往感染过OT、RT和斑点热群立克次体。与SFGR（11.6%）相比，入住城市医院的患者中OT（43.5%）和RT（22.9%）的血清流行率较高。分别在16.8%、12.7%和8.2%的患者中检测到提示近期感染恙虫病、鼠型斑疹伤寒和蜱传斑疹伤寒的抗体水平。来自2个地理位置的城市患者中，立克次体抗体分布无显著差异。然而，城市地区立克次体感染的血清学模式与农村地区不同。