Kittigul Leera, Suankeow Kedsuda, Sujirarat Dusit, Yoksan Sutee
Department of Microbiology, Faculty of Public Health, Mahidol University, Bangkok, Thailand.
Southeast Asian J Trop Med Public Health. 2003 Jun;34(2):385-92.
A cross-sectional study was carried out between July 1998 and June 1999 to identify dengue virus-infected patients under age 15 admitted to seven government hospitals in Ang Thong Province, a central region of Thailand, and to assess the knowledge, attitude, and practice (KAP) of their care takers. To differentiate dengue cases, clinical evaluation and laboratory diagnosis were used. Serum samples were collected from 90 admitted children and also from 80 healthy students. The dengue cases were classified as dengue fever (9 cases, 12.2%) and dengue hemorrhagic fever (DHF: 65 cases, 87.8%). Nine patients had dengue shock syndrome, but no death occurred. With serological confirmation, primary antibody response was observed in 8 (11.3%) and definite secondary infection in 49 (69%). Out of 41 serum samples, 14 (34.1%) were positive for dengue virus isolation: dengue serotypes 1, 2 or 3. A total of 131 care takers of enrolled children were interviewed in the context of KAP in DHF. The majority of them were mothers with primary school education level. Half of the care takers were workers. DHF knowledge of the care takers of the dengue cases, non-cases, and healthy students was almost the same. However, the care takers of dengue cases recognized petechiae as a danger sign, p-value of 0.006. They had a higher response in prevention, control and treatment of DHF than the other two groups after their children were admitted to hospital, p-value of 0.000. The results indicated that DHF remains a public health problem in this area and the people need more understanding of the disease. Continuous campaigns are required for community participation so as to prevent and control DHF successfully.
1998年7月至1999年6月期间开展了一项横断面研究,以确定泰国中部地区通廊府7家政府医院收治的15岁以下登革病毒感染患者,并评估其看护人员的知识、态度和行为(KAP)。为鉴别登革热病例,采用了临床评估和实验室诊断方法。从90名入院儿童以及80名健康学生中采集了血清样本。登革热病例分为登革热(9例,12.2%)和登革出血热(DHF:65例,87.8%)。9名患者出现登革休克综合征,但无死亡病例。经血清学确认,8例(11.3%)出现初次抗体反应,49例(69%)为明确的二次感染。在41份血清样本中,14份(34.1%)登革病毒分离呈阳性:登革1型、2型或3型。在登革出血热的KAP背景下,共对131名登记儿童的看护人员进行了访谈。他们大多数是小学文化程度的母亲。一半的看护人员是工人。登革热病例、非病例和健康学生的看护人员对登革出血热的知识几乎相同。然而,登革热病例的看护人员将瘀点视为危险信号,p值为0.006。在其子女入院后,他们在登革出血热的预防、控制和治疗方面的反应比其他两组更高,p值为0.000。结果表明,登革出血热在该地区仍是一个公共卫生问题,人们需要对该疾病有更多了解。需要持续开展宣传活动以促进社区参与,从而成功预防和控制登革出血热。