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对印度城市人口进行的系列流行病学调查表明,社会经济地位较低阶层的冠心病危险因素在增加。

Serial epidemiological surveys in an urban Indian population demonstrate increasing coronary risk factors among the lower socioeconomic strata.

作者信息

Gupta R, Gupta V P, Sarna M, Prakash H, Rastogi Shweta, Gupta K D

机构信息

Monilek Hospital and Research Centre, Jaipur, 302004.

出版信息

J Assoc Physicians India. 2003 May;51:470-7.

Abstract

OBJECTIVE

To determine trends of coronary risk factors in an Indian urban population and their association with educational level as marker of socioeconomic status.

METHODS

Two successive coronary risk factor surveys were performed in randomly selected individuals. In the first study (in 1995) 2212 subjects (1415 men, 797 women) and in the second (in 2002) 1123 subjects (550 men, 573 women) were studied. Details of smoking, physical activity, hypertension, diabetes, coronary heart disease, body-mass index, waist-hip ratio, blood pressure and electrocardiography were evaluated. Fasting blood was examined for lipid levels in 297 (199 men, 98 women) in the first and in 1082 (532 men, 550 women) in the second study. Educational status was classified into Group 0: no formal education, Group I: 1-10 years, Group II: 11-15 years, and Group III: > 16 years. Current definitions were used for risk factors in both the studies.

RESULTS

Prevalence of coronary risk factors, adjusted for age and educational status, in the first and second study in men was smoking/tobacco in 38.7 vs. 40.5%, leisure time physical inactivity in 70.8 vs. 66.1%, hypertension (> or = 140 and/or 90 mm Hg) in 29.5 vs. 33.7%, diabetes history in 1.1 vs. 7.8%, obesity (body-mass index > or = 25 Kg/m2) in 20.7 vs. 33.0%, and truncal obesity (waist:hip > 0.9) in 54.7 vs. 54.4%. In women, tobacco use was in 18.7 vs. 20.5%, leisure time physical inactivity in 72.4 vs. 75.3%, hypertension in 36.9 vs. 33.7%, diabetes history in 1.0 vs. 7.3%, obesity in 19.9 vs. 39.4%, and truncal obesity (waist:hip > 0.8) in 70.1 vs. 69.2%. In men, high total cholesterol > or = 200 mg/dl was in 24.6 vs. 37.4%, high LDL cholesterol > or = 130 mg/dl in 22.1 vs. 37.0%, high triglycerides > or = 150 mg/dl in 26.6 vs. 30.6% and low HDL cholesterol < 40 mg/dl in 43.2 vs. 54.9%; while in women these were in 22.5 vs. 43.1%, 28.6 vs. 45.1%, 28.6 vs. 28.7% and 45.9 vs. 54.2% respectively. In the second study there was a significant increase in diabetes, obesity, hypertension (men), total- and LDL cholesterol and triglycerides and decrease in HDL cholesterol (p < 0.05). In the first study with increasing educational status a significant increase of obesity, total cholesterol, LDL cholesterol and triglycerides and decrease in smoking was observed. In the second study increasing education was associated with decrease in smoking, leisure-time physical inactivity, total and LDL cholesterol, and triglycerides and increase in obesity, truncal obesity and hypertension (Least-squares regression p < 0.05). Increase in smoking, diabetes and dyslipidaemias was greater in the less educated groups.

CONCLUSIONS

Significant increase in coronary risk factors--obesity, diabetes, total-, LDL-, and low HDL cholesterol, and triglycerides is seen in this urban Indian population over a seven year period. Smoking, diabetes and dyslipidaemias increased more in low educational status groups.

摘要

目的

确定印度城市人口中冠状动脉危险因素的趋势及其与作为社会经济地位标志的教育水平之间的关联。

方法

对随机选取的个体进行了两次连续的冠状动脉危险因素调查。在第一项研究(1995年)中,研究了2212名受试者(1415名男性,797名女性),在第二项研究(2002年)中,研究了1123名受试者(550名男性,573名女性)。评估了吸烟、身体活动、高血压、糖尿病、冠心病、体重指数、腰臀比、血压和心电图的详细情况。在第一项研究中,对297名(199名男性,98名女性)进行了空腹血脂检查,在第二项研究中,对1082名(532名男性,550名女性)进行了检查。教育状况分为0组:未接受正规教育;I组:1 - 10年;II组:11 - 15年;III组:> 16年。两项研究均采用当前的危险因素定义。

结果

在第一项和第二项研究中,经年龄和教育状况调整后,男性冠状动脉危险因素的患病率分别为:吸烟/使用烟草38.7%对40.5%,休闲时间身体活动不足70.8%对66.1%,高血压(≥140和/或90 mmHg)29.5%对33.7%,糖尿病史1.1%对7.8%,肥胖(体重指数≥25 Kg/m²)20.7%对33.0%,躯干肥胖(腰臀比> 0.9)54.7%对54.4%。女性的情况分别为:使用烟草18.7%对20.5%,休闲时间身体活动不足72.4%对75.3%,高血压36.9%对33.7%,糖尿病史1.0%对7.3%,肥胖19.9%对39.4%,躯干肥胖(腰臀比> 0.8)70.1%对69.2%。在男性中,总胆固醇≥200 mg/dl为24.6%对37.4%,低密度脂蛋白胆固醇≥130 mg/dl为22.1%对37.0%,甘油三酯≥150 mg/dl为26.6%对30.6%,高密度脂蛋白胆固醇< 40 mg/dl为43.2%对54.9%;而女性分别为22.5%对43.1%,28.6%对45.1%,28.6%对28.7%,45.9%对54.2%。在第二项研究中,糖尿病、肥胖、高血压(男性)、总胆固醇和低密度脂蛋白胆固醇以及甘油三酯显著增加,高密度脂蛋白胆固醇降低(p < 0.05)。在第一项研究中,随着教育水平的提高,肥胖、总胆固醇、低密度脂蛋白胆固醇和甘油三酯显著增加,吸烟减少。在第二项研究中,教育程度的提高与吸烟、休闲时间身体活动不足、总胆固醇和低密度脂蛋白胆固醇以及甘油三酯的减少以及肥胖、躯干肥胖和高血压的增加相关(最小二乘回归p < 0.05)。在受教育程度较低的群体中,吸烟、糖尿病和血脂异常的增加更为明显。

结论

在这一印度城市人口中,七年期间冠状动脉危险因素——肥胖、糖尿病、总胆固醇、低密度脂蛋白胆固醇、低高密度脂蛋白胆固醇和甘油三酯显著增加。吸烟、糖尿病和血脂异常在低教育水平群体中增加得更多。

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