Vaquero M B
Consejería de Sanidad de la Comunidad Autónoma de Madrid. Madrid. España.
Gac Sanit. 2003 Jul-Aug;17(4):296-301. doi: 10.1016/s0213-9111(03)71750-6.
To verify and quantify, for a given active principle (omeprazole 20 mg) and for selected primary care physicians and pharmacies, the extent to which the drug prescribed on official national health system prescription forms coincides with the drug dispensed or whether the drug was dispensed following the pharmacist's criteria because the prescription was drafted in terms of the official Spanish denomination (OSD). In either case, the cost of the prescription is expressed in terms of the defined daily dose (DDD).
We reviewed 592 public health service prescriptions for omeprazole 20 mg, prescribed by 56 primary care physicians with a high prescription rate for this active principle, which were dispensed in 16 pharmacies.
Prescriptions dispensed according to the physician's prescription (50% of the prescriptions) were cheaper than those expressed in OSD and dispensed as generic drugs by pharmacists using their own criteria (36% of the cases). In all cases of substitution of the prescribed drugs (14% of prescriptions), a generic drug was dispensed and 76% of these were more expensive than the prescribed drug.
The results show that primary care physicians tend to take into account the cost of the drug and to choose cheaper drugs even when these are not generic. When pharmacists substitute the prescribed drug, they tend to dispense a generic drug that is more expensive.
对于给定的活性成分（20毫克奥美拉唑）以及选定的基层医疗医生和药房，核实并量化国家官方卫生系统处方单上开具的药物与所配发药物的相符程度，或者由于处方是按照西班牙官方名称开具的，药物是否按照药剂师的标准配发。在任何一种情况下，处方费用均以限定日剂量（DDD）表示。
我们查阅了56位基层医疗医生开具的592份20毫克奥美拉唑的公共卫生服务处方，这些医生对该活性成分的处方率较高，处方在16家药房配发。
根据医生处方配发的处方（占处方的50%）比按照西班牙官方名称开具并由药剂师根据自身标准作为非专利药品配发的处方便宜（占病例的36%）。在所有替换所开药物的情况中（占处方的14%），配发的是非专利药品，其中76%比所开药物更贵。
结果表明，基层医疗医生倾向于考虑药物成本并选择较便宜的药物，即使这些药物不是非专利药品。当药剂师替换所开药物时，他们倾向于配发更昂贵的非专利药品。
