Bonk U, Occhionero F
Z Krebsforsch Klin Onkol Cancer Res Clin Oncol. 1976 Jan 2;85(1):13-20. doi: 10.1007/BF00308124.
In 6000 cases of hysterectomy nine adenomatoid tumors of myometrium were observed. Macroscopically, the adenomatoid tumour appears as a round or ovoid mass of grey or whitegrey colour about the size of a hazel-nut. Microscopically, four types are distinguished: solid, angiomatoid, macrotubular and mixed types. The cytoplasma of the cells tends to be vacuolated, the glandlike spaces being probably derived by confluence of these vacuoles. The interstitial tissue contains cells of the same type and often lymphocytes. Several hypotheses concerning the histogenesis of adenomatoid tumors are reviewed. The adenomatoid tumor is more frequent in the myometrium than it has been hitherto known. Probably the tumor is often misinterpreted as leiomyoma of the uterus on the basis of macroscopical appearance only.
在6000例子宫切除术中,观察到9例子宫肌层腺瘤样肿瘤。大体上,腺瘤样肿瘤表现为圆形或卵圆形肿块,呈灰色或灰白色,大小约为榛子。显微镜下可分为四种类型:实性、血管瘤样、大管状和混合型。细胞的细胞质往往呈空泡状,腺样间隙可能由这些空泡融合而成。间质组织含有相同类型的细胞,且常伴有淋巴细胞。本文综述了几种关于腺瘤样肿瘤组织发生的假说。腺瘤样肿瘤在子宫肌层中比迄今所知更为常见。可能该肿瘤常仅基于大体外观而被误诊为子宫平滑肌瘤。