[Approach to studying the structure-activity relationship of native peptides. II. Structural organization of alpha- and beta-neoendorphins].

By means of a semi-empirical method, an a priori conformational analysis of alpha- and beta-neo-endorphins was carried out. Calculations yielded the values of all dihedral angles of the backbone and side chains of the peptide's various forms as well as intra- and inter-residue interaction energies.