Seiferth J
Fortschr Med. 1977 Jan 13;95(2):103-6.
From the view of the urological diseases a new conception of the spina bifida cystica is represented. The first part contains informations on etiology, pathological anatomy and physio-pathology. Considering the urological diseases (neurogenic bladder with incontinence and residual urine, vesico ureteric reflux and chronic pyelonephritis) special importance is attached to the pathogenesis. Within the therapeutic methods the treatment with the alpha-blocking agent Phenoxybenzamin (Dibenzyran, Röhm Pharma GmbH, Darmstadt) is emphasized as the actual therapy of the neurogenic bladder. The operative indication of the Ileum-Conduit (Bricker-) is mentioned. An analysis of 125 spina bifida-patients with the pathological findings in the kidneys and the urinary tract is given.
从泌尿系统疾病的角度出发，提出了关于脊柱裂囊肿的新观念。第一部分包含病因学、病理解剖学和生理病理学方面的信息。考虑到泌尿系统疾病（伴有尿失禁和残余尿的神经源性膀胱、膀胱输尿管反流和慢性肾盂肾炎），发病机制具有特殊重要性。在治疗方法中，强调使用α阻滞剂苯氧苄胺（双苄胺，德国达姆施塔特的罗姆制药有限公司）作为神经源性膀胱的实际治疗方法。提到了回肠代膀胱术（布里克尔术式）的手术指征。给出了125例脊柱裂患者肾脏和尿路病理检查结果的分析。
