Caron P, Guittard J, Trouillas J, Salvador M, Bayard F
Service d'Endocrinologie et Maladies Métaboliques, CHU Ranguei, Toulouse.
Ann Endocrinol (Paris). 1992;53(4):158-61.
Acromegaly due to ectopic secretion of growth hormone-releasing hormone (GHRH) is rare. A 29-year-old woman with acromegaly secondary to ectopic GHRH secretion by a bronchial carcinoid tumor is presented. Normalization of GHRH levels, reversal of pituitary hyperplasia and regression of acromegaly followed resection of the bronchial tumor. The authors stressed the interest of GHRH dosage in patients with acromegaly and pituitary hyperplasia.
由异位分泌生长激素释放激素(GHRH)引起的肢端肥大症很罕见。本文报告了一名29岁女性,因支气管类癌肿瘤异位分泌GHRH继发肢端肥大症。切除支气管肿瘤后,GHRH水平恢复正常,垂体增生逆转,肢端肥大症消退。作者强调了GHRH剂量测定在肢端肥大症和垂体增生患者中的意义。