骨佩吉特病中的恶性纤维组织细胞瘤。7例报告。

Malignant fibrous histiocytoma in Paget's disease of bone. A report of seven cases.

作者信息

Cossetto D, Nade S, Blackwell J

机构信息

Department of Surgery (Orthopaedic Surgery), Westmead Hospital Sydney, New South Wales, Australia.

出版信息

Aust N Z J Surg. 1992 Jan;62(1):52-5. doi: 10.1111/j.1445-2197.1992.tb05354.x.

DOI:10.1111/j.1445-2197.1992.tb05354.x

PMID:1310002

Abstract

Malignant change in Paget's disease of bone usually has the histological features of osteosarcoma, but follows a different clinical course from cases not associated with paget's disease of bone. Malignant fibrous histiocytoma is an uncommon neoplasm which may be associated with pagetic bone and its clinical course is not well defined. Seven cases of malignant fibrous histiocytoma in Paget's disease were reviewed from two Australian bone tumour registries. In stage IIB and III disease there was a three year survival rate of 57%, suggesting a better prognosis than for patients with other sarcomas in Paget's disease.

摘要

骨佩吉特病的恶变通常具有骨肉瘤的组织学特征，但临床病程与非骨佩吉特病相关的病例不同。恶性纤维组织细胞瘤是一种罕见的肿瘤，可能与佩吉特骨有关，其临床病程尚不明确。从两个澳大利亚骨肿瘤登记处回顾了7例佩吉特病中的恶性纤维组织细胞瘤病例。在IIB期和III期疾病中，三年生存率为57%，提示预后比佩吉特病中其他肉瘤患者更好。