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儿科内分泌学;近期一些进展的笔记

Pediatric endocrinology; notes on some recent advances.

作者信息

PLACHTE F L

出版信息

Calif Med. 1953 Nov;79(5):353-6.

Abstract

Until recently, congenital adrenocortical hyperplasia has defied most medical and surgical therapeutic efforts. However, in properly selected patients, cortisone will suppress the abnormal cortical hormone production. This, in turn, will lead to previously inhibited maturation and developmental progress. Adrenocortical insufficiency calls for much diagnostic alertness, as early recognition and immediate treatment are of paramount importance. The available therapeutic means are beneficial, although their limitations and potential dangers should be heeded.Among newly developed diagnostic techniques, thyrograms promise to be helpful in the study of thyroid hyperplasia and neoplasia. Thyroid cancer, occurring infrequently in childhood, should at the earliest possible time be treated surgically and with postoperative radiation therapy.

摘要

直到最近,先天性肾上腺皮质增生症仍使大多数药物和手术治疗手段束手无策。然而,对于经过恰当挑选的患者,可的松会抑制异常的皮质激素分泌。这继而会促使此前受到抑制的成熟和发育进程得以推进。肾上腺皮质功能不全需要高度的诊断警觉性,因为早期识别和及时治疗至关重要。现有的治疗手段虽有益处,但也应注意其局限性和潜在风险。在新研发的诊断技术中,甲状腺造影术有望有助于甲状腺增生和肿瘤的研究。甲状腺癌在儿童时期很少见,一旦发现应尽早进行手术治疗并辅以术后放射治疗。

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本文引用的文献

1
Adrenal insufficiency in infancy; a clinical classification, review, and a report of a case.
J Pediatr. 1950 Jul;37(1):1-22. doi: 10.1016/s0022-3476(50)80002-1.
2
Carcinoma of the thyroid in children; a 10 year follow-up.
Radiology. 1950 Mar;54(3):401-7. doi: 10.1148/54.3.401.
3
Adrenocortical hypoplasia in the newborn infant; report of a case with replacement therapy.
N Engl J Med. 1950 Jan 19;242(3):87-9, illust. doi: 10.1056/NEJM195001192420303.

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