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维特罗辛:胶原蛋白家族的一员。

Vitrosin: a member of the collagen class.

作者信息

GROSS J, MATOLTSY G, COHEN C

出版信息

J Biophys Biochem Cytol. 1955 May 25;1(3):215-20. doi: 10.1083/jcb.1.3.215.

Abstract

Vitrosin, a fibrous protein obtained from the vitreous humor of the eye in the form of an indefinitely long fibril about 100 to 150 A in diameter, has been identified as a member of the collagen class of proteins. It is characterized by the collagen wide-angle x-ray diffraction pattern, and axial periodicity of about 640 A determined by electron microscopy and small-angle x-ray diffraction, an amino acid pattern characteristic of collagen as determined by paper chromatography, and a hydroxyproline and glycine content also typical of collagen. The glycine-hydroxyproline ratio is somewhat lower than that for most vertebrate collagens.

摘要

玻璃素是一种从眼玻璃体液中获取的纤维状蛋白质,呈直径约100至150埃的无限长原纤维形式,已被鉴定为胶原蛋白类蛋白质的一员。它的特征在于具有胶原蛋白的广角X射线衍射图谱,通过电子显微镜和小角X射线衍射测定的约640埃的轴向周期性,通过纸色谱法测定的具有胶原蛋白特征的氨基酸模式,以及同样典型的胶原蛋白的羟脯氨酸和甘氨酸含量。甘氨酸与羟脯氨酸的比例略低于大多数脊椎动物胶原蛋白的该比例。

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