近平滑念珠菌引起的心内膜炎。

Endocarditis caused by Candida parapsilosis.

作者信息

Senba M, Watanabe K, Yoshida K, Ochi S, Matsumoto K, Yano K, Itakura H

机构信息

Department of Pathology, Nagasaki University, Japan.

出版信息

Southeast Asian J Trop Med Public Health. 1992 Mar;23(1):138-41.

PMID:1326123

Abstract

The authors report a case of endocarditis caused by Candida parapsilosis. To the best of our knowledge, a case has not been described previously in Japan in the English literature. A battery of 8 peroxidase-labeled lectins was tested on sections of paraffin-embedded tissue to determine which lectin could be used in the microscopic diagnosis of C. parapsilosis. One lectin, from Archis hypoaea (PNA) was found to react with C. parapsilosis. On the other hand, C. albicans, Aspergillus, Mucor, and Cryptococcus did not react with A. hypoaea (PNA). On fluorescence microscopic study, C. parapsilosis was not fluorescent, but other fungi were fluorescent when exposed to ultraviolet illumination. Therefore, we propose new procedures for identification of C. parapsilosis in tissue sections using lectin histochemistry and fluorescence microscopy.

摘要

作者报告了1例近平滑念珠菌引起的心内膜炎病例。据我们所知，日本英文文献中此前尚未描述过此类病例。对一系列8种过氧化物酶标记的凝集素在石蜡包埋组织切片上进行了检测，以确定哪种凝集素可用于近平滑念珠菌的显微镜诊断。发现一种来自花生（PNA）的凝集素可与近平滑念珠菌发生反应。另一方面，白色念珠菌、曲霉、毛霉和隐球菌与花生（PNA）不发生反应。在荧光显微镜研究中，近平滑念珠菌不发荧光，但其他真菌在紫外线照射下会发荧光。因此，我们提出了利用凝集素组织化学和荧光显微镜在组织切片中鉴定近平滑念珠菌的新方法。