一些关于非普拉宗的研究。

Some studies of feprazone.

作者信息

Haslock I, Burkinshaw L, Berry D J, Donovan B, Wright V

出版信息

Rheumatol Rehabil. 1976 May;15(2):81-6. doi: 10.1093/rheumatology/15.2.81.

DOI:10.1093/rheumatology/15.2.81

Abstract

Feprazone, 200 mg t.d.s., was compared with indomethacin, 25 mg t.d.s. rising to 50 mg t.d.s., in an eight-week double-blind cross-over study in twenty-three patients with active rheumatoid arthritis. Both therapies proved equally efficacious and acceptable. Measurement of the plasma levels of the two drugs showed no consistent correlation between efficacy and plasma concentrations.

摘要

在一项针对23名活动性类风湿性关节炎患者的为期八周的双盲交叉研究中，对每日三次服用200毫克非普拉宗与每日三次服用25毫克消炎痛（后增至每日三次50毫克）进行了比较。两种疗法均证明同样有效且可接受。对两种药物血浆水平的测量表明，疗效与血浆浓度之间没有一致的相关性。