ASKEY J M, CHERRY C B
Calif Med. 1956 Jan;84(1):16-7.
Extraction of 14 teeth in six patients taking dicumarol caused no unusual bleeding. Discontinuance of dicumarol prior to dental extraction should not necessarily be a routine procedure; in certain persons with a demonstrated strong tendency to recurrent thrombosis, dicumarol should be continued, based on the decision that the danger of clotting without the drug is greater than the danger of bleeding with the drug.
6名服用双香豆素的患者拔除14颗牙齿后未出现异常出血情况。拔牙前不一定非要常规停用双香豆素;对于某些已证实有反复血栓形成强烈倾向的患者,基于无药物时凝血的风险大于用药时出血风险的判断,应继续使用双香豆素。