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[锝(Ⅴ)二巯基丁二酸对头颈部癌症的闪烁成像。一项前瞻性临床研究]

[Scintigraphic imaging of head and neck cancers with 99m technetium (v) dimercaptosuccinic acid. A prospective clinical study].

作者信息

Heinritz H, Marienhagen J, Wolf F, Schuster B, Stenglein C, Iro H

机构信息

Klinik und Poliklinik für Hals-Nasen-Ohrenkranke.

出版信息

HNO. 1992 Nov;40(11):437-41.

PMID:1335446
Abstract

In patients with cervical metastases conventional examination by ultrasound, CT or MRI imaging often fails to identify an unknown primary tumor. Also the retrieval of a recurrent malignancy may be difficult. Scintigraphy, utilizing technetium-99m (v) dimercaptosuccinic acid was chosen for a prospective study in 17 patients to evaluate its properties for imaging metastasizing squamous cell carcinoma of the head and neck. Scintigraphic findings were correlated with the results of clinical examination and conventional imaging techniques. In all cases the primary tumor revealed good uptake of 99mTc(v)DMSA. Manifest cervical metastases could only be imaged in some cases. In future, therefore, 99mTc(v)DMSA scanning may be used for the detection of unknown primary tumors. However, it does not appear helpful in the evaluation of cervical nodes.

摘要

在患有颈部转移瘤的患者中,通过超声、CT或MRI成像进行的传统检查往往无法识别出未知的原发肿瘤。此外,复发性恶性肿瘤的检出也可能很困难。选择利用锝-99m(V)二巯基丁二酸进行闪烁扫描,对17例患者进行前瞻性研究,以评估其对头颈部转移性鳞状细胞癌的成像特性。闪烁扫描结果与临床检查结果和传统成像技术的结果相关。在所有病例中,原发肿瘤均显示出对99mTc(V)DMSA的良好摄取。仅在某些病例中可对明显的颈部转移瘤进行成像。因此,未来99mTc(V)DMSA扫描可用于检测未知的原发肿瘤。然而,它在评估颈部淋巴结方面似乎并无帮助。

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