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[甲状旁腺激素对饮用低钙低镁水大鼠心肌机械活动影响的特点]

[The characteristics of the effect of parathyroid hormone on the mechanical activity of the myocardium in rats with a deficiency of Ca and Mg in the drinking water].

作者信息

Barabanova T A, Markhasin V S, Nikitina L V, Churina S K

出版信息

Fiziol Zh SSSR Im I M Sechenova. 1992 Jul;78(7):71-7.

PMID:1335899
Abstract

Inotropic and lusitropic effects of the parathyroid hormone (PTH) upon the rat heart ventricle myocardium were studied in conditions of calcium and magnesium deficit in drinking water. The control rats revealed two phases of the hormone effect: the positive and negative ones, whereas the experimental rats only revealed the negative inotropic effect. Both the negative and positive inotropic effects were followed by an acceleration of the relaxation.

摘要

在饮用水中钙和镁缺乏的条件下,研究了甲状旁腺激素(PTH)对大鼠心室心肌的变力性和变时性作用。对照大鼠显示出激素作用的两个阶段:正性和负性阶段,而实验大鼠仅显示出负性变力作用。负性和正性变力作用之后均伴随着舒张加速。

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