RAKSANYI A, SOS J, SZABO G
Bull World Health Organ. 1956;15(1-2):317-27.
Studies on the extent and severity of endemic goitre-a serious public health problem in Hungary-have been carried out in that country since 1925, but by uniform methods since 1943 only. They show that over 400 000 persons suffer from goitre or other thyroid disorders, which are endemic in about 20% of the country, although only 8% of the affected areas are mountainous. Research into the proper level of iodization for salt was conducted on about 9000 persons, and it was decided to use 10 mg KI per kg of salt. In 1949, the use of iodized salt was made compulsory in areas where the frequency of goitre among schoolboys 6-10 years of age was 20% or higher or where signs of physical and mental degeneration were frequent. In other areas, the use of iodized salt was optional. Over six years, a significant improvement has occurred in most of the areas with compulsory iodization. Where there has been no significant improvement more detailed etiological studies are necessary; this can only be done by introducing a more local system of control with goitre subcentres, and work on these lines has already begun.The object of goitre prophylaxis in Hungary is to reduce the incidence of the disease to below 1%, when more purely therapeutic measures can be taken.
自1925年以来,匈牙利一直在对地方性甲状腺肿(该国一个严重的公共卫生问题)的范围和严重程度进行研究,但仅从1943年起采用统一方法。研究表明,超过40万人患有甲状腺肿或其他甲状腺疾病,这些疾病在该国约20%的地区流行,尽管受影响地区中只有8%是山区。对约9000人进行了食盐适当碘化水平的研究,决定每千克盐使用10毫克碘化钾。1949年,在6至10岁男学生甲状腺肿发病率达20%或更高,或身心退化迹象频繁出现的地区,强制使用加碘盐。在其他地区,加碘盐的使用为自愿选择。六年来,在大多数强制碘化的地区已出现显著改善。在未取得显著改善的地方,需要进行更详细的病因学研究;这只能通过引入一个有甲状腺肿防治分中心的更本地化的控制系统来完成,并且这方面的工作已经开始。匈牙利甲状腺肿预防的目标是将该病发病率降至1%以下,届时便可采取更纯粹的治疗措施。