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促性腺激素释放激素类似物与多囊卵巢疾病:长效醋酸亮丙瑞林微球在该疾病治疗中的应用有效性

LHRH analogues and PCO disease: validity of the use of enantone depot in the treatment of the disease.

作者信息

Vitale F, Ruggieri P

机构信息

Chair of Obstetrical and Gynaecological Pathology, University of Bari, Italy.

出版信息

Acta Eur Fertil. 1992 Nov-Dec;23(6):293-5.

PMID:1343754
Abstract

The Authors have been showed the utility of LHRH analogues in the treatment of PCO disease, through hormonal dosages and echographic examination made before, during and after the therapy both with Enantone depot, CPA and EE2, and with only CPA and EE2 of control cases. The association of analogue to traditional therapy has determined a more speedy reduction of haematic levels of LH, T free, DHEA-S, than the ones we have found in control case, an evident reduction (50%) of pilonidal growth and an important improvement of acne and seborrhea.

摘要

作者通过对使用长效庚酸睾酮、醋酸氯羟甲烯孕酮和炔雌醇(EE2)治疗以及仅使用醋酸氯羟甲烯孕酮和炔雌醇的对照病例在治疗前、治疗期间和治疗后的激素剂量测定和超声检查,展示了促性腺激素释放激素(LHRH)类似物在多囊卵巢(PCO)疾病治疗中的效用。与传统疗法联合使用类似物已导致促黄体生成素(LH)、游离睾酮(T)、硫酸脱氢表雄酮(DHEA-S)的血液水平比我们在对照病例中发现的水平下降得更快,多毛症明显减少(50%),痤疮和脂溢性皮炎有显著改善。

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