Rodríguez-Ojea Menéndez A, García de la Osa M
Brigada Medica Cubana, Republica Popular Benin.
Rev Cubana Med Trop. 1992;44(1):62-5.
A study was carried out on susceptibility of sicklemia patients to Plasmodium falciparum (PF) malaria in 151 hemoglobin S carriers (homozygous and heterozygous), assisted at the Cotonú Hospital, Benin, for 1 year. These diseased did not have any serious malaria complications. The results were compared to a control group without sickle-cell anemia who had 21.5% of complications due to the disease. Prevalence of genetic anomaly was higher than 20% among the general population under study.
在贝宁科托努医院对151名血红蛋白S携带者(纯合子和杂合子)镰状血症患者对恶性疟原虫(PF)疟疾的易感性进行了为期1年的研究。这些患者没有任何严重的疟疾并发症。将结果与没有镰状细胞贫血的对照组进行比较,该对照组因该疾病出现并发症的比例为21.5%。在所研究的普通人群中,遗传异常的患病率高于20%。