MYERSCOUGH P R, SCHILD H O
Br J Pharmacol Chemother. 1958 Jun;13(2):207-12. doi: 10.1111/j.1476-5381.1958.tb00219.x.
Quantitative assays of oxytocic drugs were performed on the postpartum human uterus by means of external tocography. Since, owing to the rapid involution of the uterus, only two doses could be given to each patient, the assays were designed as incomplete randomized blocks of 2. A dose/response curve for ergometrine was established, and a comparative assay of ergometrine and methly ergometrine carried out, the design and analysis of which is described in detail.
采用外部宫缩图对产后人体子宫进行催产药物的定量测定。由于子宫迅速复旧,每位患者仅能给予两剂药物,因此测定设计为每组2例的不完全随机区组。建立了麦角新碱的剂量-反应曲线,并对麦角新碱和甲基麦角新碱进行了对比测定,其设计和分析将详细描述。